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Multi-spectroscopic, thermodynamic, and molecular docking/dynamic approaches for characterization of the binding interaction between calf thymus DNA and palbociclib

Studying the binding interaction between biological macromolecules and small molecules has formed the core of different research aspects. The interaction of palbociclib with calf thymus DNA at simulated physiological conditions (pH 7.4) was studied using different approaches, including spectrophotom...

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Detalles Bibliográficos
Autores principales: Magdy, Galal, Shaldam, Moataz A., Belal, Fathalla, Elmansi, Heba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427788/
https://www.ncbi.nlm.nih.gov/pubmed/36042232
http://dx.doi.org/10.1038/s41598-022-19015-9