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Mapping the association between tau-PET and Aβ-amyloid-PET using deep learning

In Alzheimer’s disease, the molecular pathogenesis of the extracellular Aβ-amyloid (Aβ) instigation of intracellular tau accumulation is poorly understood. We employed a high-resolution PET scanner, with low detection thresholds, to examine the Aβ-tau association using a convolutional neural network...

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Detalles Bibliográficos
Autores principales: Ruwanpathirana, Gihan P., Williams, Robert C., Masters, Colin L., Rowe, Christopher C., Johnston, Leigh A., Davey, Catherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427855/
https://www.ncbi.nlm.nih.gov/pubmed/36042256
http://dx.doi.org/10.1038/s41598-022-18963-6