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A multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress
The minichromosome maintenance (MCM) 8/9 helicase is a AAA(+) complex involved in DNA replication-associated repair. Despite high sequence homology to the MCM2-7 helicase, a precise cellular role for MCM8/9 has remained elusive. We have interrogated the DNA synthesis ability and replication fork sta...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427862/ https://www.ncbi.nlm.nih.gov/pubmed/36042199 http://dx.doi.org/10.1038/s41467-022-32583-8 |