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p53 positively regulates the proliferation of hepatic progenitor cells promoted by laminin-521

Hepatic progenitor cells (HPCs) hold tremendous potential for liver regeneration, but their well-known limitation of proliferation hampers their broader use. There is evidence that laminin is required for the proliferation of HPCs, but the laminin isoform that plays the dominant role and the key int...

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Detalles Bibliográficos
Autores principales: Ma, Mingyang, Hua, Shuyao, Min, Xiangde, Wang, Liang, Li, Jun, Wu, Ping, Liang, Huifang, Zhang, Bixiang, Chen, Xiaoping, Xiang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427945/
https://www.ncbi.nlm.nih.gov/pubmed/36042225
http://dx.doi.org/10.1038/s41392-022-01107-7