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Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma

For patients with platinum-resistant lung adenocarcinoma (LUAD), the exploration of new effective drug candidates is urgently needed. Fibroblast growth factor receptors (FGFRs) have been identified as promising targets for LUAD therapy. The purpose of this study was to determine the exact role of th...

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Detalles Bibliográficos
Autores principales: Jia, Xiuqin, Xin, Ming, Xu, Juanjuan, Xiang, Xindong, Li, Xuan, Jiao, Yuhan, Wang, Lulin, Jiang, Jingjing, Pang, Feng, Zhang, Xianzhen, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428205/
https://www.ncbi.nlm.nih.gov/pubmed/36042213
http://dx.doi.org/10.1038/s41419-022-05201-0