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Novel Phenobarbital-Loaded Nanostructured Lipid Carriers for Epilepsy Treatment: From QbD to In Vivo Evaluation

Pharmacological treatments of central nervous system diseases are always challenging due to the restrictions imposed by the blood–brain barrier: while some drugs can effectively cross it, many others, some antiepileptic drugs among them, display permeability issues to reach the site of action and ex...

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Detalles Bibliográficos
Autores principales: Scioli-Montoto, Sebastian, Sbaraglini, Maria Laura, Cisneros, Jose Sebastian, Chain, Cecilia Yamil, Ferretti, Valeria, León, Ignacio Esteban, Alvarez, Vera Alejandra, Castro, Guillermo Raul, Islan, German Abel, Talevi, Alan, Ruiz, Maria Esperanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428247/
https://www.ncbi.nlm.nih.gov/pubmed/36059881
http://dx.doi.org/10.3389/fchem.2022.908386