Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution

PURPOSE: Retinal pericytes play a vital role in maintaining retinal homeostasis, and their dysfunction underlies pathogenesis in such vascular eye diseases as diabetic retinopathy and wet age-related macular degeneration. Consequently, retinal pericytes are attractive therapeutic targets for gene th...

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Detalles Bibliográficos
Autores principales: Patel, Dwani D., Marsic, Damien, Periasamy, Ramesh, Zolotukhin, Sergei, Lipinski, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428359/
https://www.ncbi.nlm.nih.gov/pubmed/36018583
http://dx.doi.org/10.1167/tvst.11.8.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428359/
https://www.ncbi.nlm.nih.gov/pubmed/36018583
http://dx.doi.org/10.1167/tvst.11.8.28

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