Cargando…

Function conservation and disparities of zebrafish and human LGP2 genes in fish and mammalian cells responsive to poly(I:C)

Retinoic acid inducible gene-I (RIG-I)-like receptors (RLRs) are viral RNA sensors that regulate host interferon (IFN)-mediated antiviral signaling. LGP2 (laboratory genetics and physiology 2) lacks the N-terminal caspase activation and recruitment domains (CARDs) responsible for signaling transduct...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Xiu-Ying, Qu, Zi-Ling, Li, Yi-Lin, Sun, Hao-Yu, Zhao, Xiang, Dan, Cheng, Gui, Jian-Fang, Zhang, Yi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428467/
https://www.ncbi.nlm.nih.gov/pubmed/36059486
http://dx.doi.org/10.3389/fimmu.2022.985792