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Downregulation of ZNF280A inhibits proliferation and tumorigenicity of colorectal cancer cells by promoting the ubiquitination and degradation of RPS14

Colorectal cancer (CRC), one of the cancers with highest mortality, involves complicated molecular mechanisms leading to the onset of malignant phenotypes. ZNF280A, a member of the zinc-finger protein family, was shown to be a promotor of oncogenesis in CRC in this study. ZNF280A was remarkably upre...

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Detalles Bibliográficos
Autores principales: Tian, Binle, Zhou, Jingyi, Chen, Guiming, Jiang, Tao, Li, Qi, Qin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428494/
https://www.ncbi.nlm.nih.gov/pubmed/36059657
http://dx.doi.org/10.3389/fonc.2022.906281