Cargando…

A synthetic ancestral kinesin-13 depolymerizes microtubules faster than any natural depolymerizing kinesin

The activity of a kinesin is largely determined by the approximately 350 residue motor domain, and this region alone is sufficient to classify a kinesin as a member of a particular family. The kinesin-13 family are a group of microtubule depolymerizing kinesins and are vital regulators of microtubul...

Descripción completa

Detalles Bibliográficos
Autores principales: Belsham, Hannah R., Alghamdi, Hanan M., Dave, Nikita, Rathbone, Alexandra J., Wickstead, Bill, Friel, Claire T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428548/
https://www.ncbi.nlm.nih.gov/pubmed/36043268
http://dx.doi.org/10.1098/rsob.220133