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Angiogenesis in NENs, with a focus on gastroenteropancreatic NENs: from biology to current and future therapeutic implications

Neuroendocrine neoplasms (NENs) are highly vascularized malignancies arising from cells of the diffuse neuroendocrine system. An intricated cross-talk exists between NEN cells and the tumor microenvironment, and three main molecular circuits (VEGF/VEGFR pathway, FGF-dependent signaling and PDGF/PDGF...

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Detalles Bibliográficos
Autores principales: Lauricella, Eleonora, Mandriani, Barbara, Cavallo, Federica, Pezzicoli, Gaetano, Chaoul, Nada, Porta, Camillo, Cives, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428554/
https://www.ncbi.nlm.nih.gov/pubmed/36059642
http://dx.doi.org/10.3389/fonc.2022.957068