Synthesis and structure–activity relationship of peptide nucleic acid probes with improved interstrand-crosslinking abilities: application to biotin-mediated RNA-pulldown

The development of interstrand-crosslinking (ICL) probes for the covalent targeting of DNA and RNA sequences of interest has been extensively reported in the past decade. However, most of the reactions reported so far induce the formation of a stable adduct that cannot be reverted, thus rendering th...

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Detalles Bibliográficos
Autores principales: Cadoni, Enrico, Pennati, Francesca, Muangkaew, Penthip, Elskens, Joke, Madder, Annemieke, Manicardi, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428673/
https://www.ncbi.nlm.nih.gov/pubmed/36128507
http://dx.doi.org/10.1039/d2cb00095d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428673/
https://www.ncbi.nlm.nih.gov/pubmed/36128507
http://dx.doi.org/10.1039/d2cb00095d

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