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Metabolic management of microenvironment acidity in glioblastoma

Glioblastoma (GBM), similar to most cancers, is dependent on fermentation metabolism for the synthesis of biomass and energy (ATP) regardless of the cellular or genetic heterogeneity seen within the tumor. The transition from respiration to fermentation arises from the documented defects in the numb...

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Detalles Bibliográficos
Autores principales: Seyfried, Thomas N., Arismendi-Morillo, Gabriel, Zuccoli, Giulio, Lee, Derek C., Duraj, Tomas, Elsakka, Ahmed M., Maroon, Joseph C., Mukherjee, Purna, Ta, Linh, Shelton, Laura, D'Agostino, Dominic, Kiebish, Michael, Chinopoulos, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428719/
https://www.ncbi.nlm.nih.gov/pubmed/36059707
http://dx.doi.org/10.3389/fonc.2022.968351