Mistimed sleep and waking activity in humans disrupts glucocorticoid signalling transcripts and SP1, but not plasma cortisol rhythms

Cortisol is a robust circadian signal that synchronises peripheral circadian clocks with the central clock in the suprachiasmatic nucleus via glucocorticoid receptors that regulate peripheral gene expression. Misalignment of the cortisol rhythm with the sleep–wake cycle, as occurs in shift work, is...

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Detalles Bibliográficos
Autores principales: Archer, Simon N., Möller-Levet, Carla S., Laing, Emma E., Dijk, Derk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428761/
https://www.ncbi.nlm.nih.gov/pubmed/36060675
http://dx.doi.org/10.3389/fphys.2022.946444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428761/
https://www.ncbi.nlm.nih.gov/pubmed/36060675
http://dx.doi.org/10.3389/fphys.2022.946444

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