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Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities

BACKGROUND: We studied clinical characteristics, survival and neurological outcomes in patients with pre-existing cardiovascular (CV) conditions who experienced an out-of-hospital cardiac arrest (OHCA). METHODS: We studied all cases of OHCA in the Swedish Registry for Cardiopulmonary Resuscitation (...

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Autores principales: Rawshani, Araz, Hessulf, Fredrik, Völz, Sebastian, Dworeck, Christian, Odenstedt, Jacob, Råmunddal, Truls, Hirlekar, Geir, Petursson, Petur, Angerås, Oskar, Ioanes, Dan, Myredal, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428786/
https://www.ncbi.nlm.nih.gov/pubmed/36059386
http://dx.doi.org/10.1016/j.resplu.2022.100294
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author Rawshani, Araz
Hessulf, Fredrik
Völz, Sebastian
Dworeck, Christian
Odenstedt, Jacob
Råmunddal, Truls
Hirlekar, Geir
Petursson, Petur
Angerås, Oskar
Ioanes, Dan
Myredal, Anna
author_facet Rawshani, Araz
Hessulf, Fredrik
Völz, Sebastian
Dworeck, Christian
Odenstedt, Jacob
Råmunddal, Truls
Hirlekar, Geir
Petursson, Petur
Angerås, Oskar
Ioanes, Dan
Myredal, Anna
author_sort Rawshani, Araz
collection PubMed
description BACKGROUND: We studied clinical characteristics, survival and neurological outcomes in patients with pre-existing cardiovascular (CV) conditions who experienced an out-of-hospital cardiac arrest (OHCA). METHODS: We studied all cases of OHCA in the Swedish Registry for Cardiopulmonary Resuscitation (2010–2020). Patients were grouped according to the following pre-existing CV conditions prior: hypertension (HT), heart failure (HF) with HT, HF with ischemic heart disease (IHD), HF without HT or IHD, IHD, myocardial infarction (MI) and diabetes mellitus (DM), with groups being mutually exclusive. We studied 30-day survival and neurological outcomes using logistic and Cox regression. RESULTS: A total of 56,203 patients were included. The lowest rates of shockable rhythm occurred in cases with HT (19%), HF and HT (18%) and DM (18%). Median time to OHCA from diagnosis of HT was 2.0 years in cases aged 0–40 years at diagnosis of HT, 4.4 years in those aged 41–60 at diagnosis, 5.0 years in those aged 61–70 years, 5.6 years in those aged 71–80 years and 6.0 years in those aged 81 years or older. The lowest survival was noted for patients with HF and HT. Age and sex adjusted OR for CPC score 1 did not differ in any group. CONCLUSION: The combination of HT and HF has the lowest survival of all cardiovascular comorbidities. Early onset of hypertension is a predictor for early cardiac arrest.
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spelling pubmed-94287862022-09-01 Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities Rawshani, Araz Hessulf, Fredrik Völz, Sebastian Dworeck, Christian Odenstedt, Jacob Råmunddal, Truls Hirlekar, Geir Petursson, Petur Angerås, Oskar Ioanes, Dan Myredal, Anna Resusc Plus Clinical Paper BACKGROUND: We studied clinical characteristics, survival and neurological outcomes in patients with pre-existing cardiovascular (CV) conditions who experienced an out-of-hospital cardiac arrest (OHCA). METHODS: We studied all cases of OHCA in the Swedish Registry for Cardiopulmonary Resuscitation (2010–2020). Patients were grouped according to the following pre-existing CV conditions prior: hypertension (HT), heart failure (HF) with HT, HF with ischemic heart disease (IHD), HF without HT or IHD, IHD, myocardial infarction (MI) and diabetes mellitus (DM), with groups being mutually exclusive. We studied 30-day survival and neurological outcomes using logistic and Cox regression. RESULTS: A total of 56,203 patients were included. The lowest rates of shockable rhythm occurred in cases with HT (19%), HF and HT (18%) and DM (18%). Median time to OHCA from diagnosis of HT was 2.0 years in cases aged 0–40 years at diagnosis of HT, 4.4 years in those aged 41–60 at diagnosis, 5.0 years in those aged 61–70 years, 5.6 years in those aged 71–80 years and 6.0 years in those aged 81 years or older. The lowest survival was noted for patients with HF and HT. Age and sex adjusted OR for CPC score 1 did not differ in any group. CONCLUSION: The combination of HT and HF has the lowest survival of all cardiovascular comorbidities. Early onset of hypertension is a predictor for early cardiac arrest. Elsevier 2022-08-24 /pmc/articles/PMC9428786/ /pubmed/36059386 http://dx.doi.org/10.1016/j.resplu.2022.100294 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical Paper
Rawshani, Araz
Hessulf, Fredrik
Völz, Sebastian
Dworeck, Christian
Odenstedt, Jacob
Råmunddal, Truls
Hirlekar, Geir
Petursson, Petur
Angerås, Oskar
Ioanes, Dan
Myredal, Anna
Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
title Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
title_full Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
title_fullStr Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
title_full_unstemmed Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
title_short Characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: A nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
title_sort characteristics, survival and neurological outcome in out-of-hospital cardiac arrest: a nationwide study of 56,203 cases with emphasis on cardiovascular comorbidities
topic Clinical Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428786/
https://www.ncbi.nlm.nih.gov/pubmed/36059386
http://dx.doi.org/10.1016/j.resplu.2022.100294
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