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Combining fecal microbiome and metabolomics to reveal the disturbance of gut microbiota in liver injury and the therapeutic mechanism of shaoyao gancao decoction

Chemical liver injury is closely related to gut microbiota and its metabolites. In this study, we combined 16S rRNA gene sequencing, (1)H NMR-based fecal metabolomics and GC-MS to evaluate the changes in gut microbiota, fecal metabolites and Short-chain fatty acids (SCFAs) in CCl(4)-induced liver in...

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Detalles Bibliográficos
Autores principales: Li, Jingwei, Zhao, Min, Li, Jianming, Wang, Miao, Zhao, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428823/
https://www.ncbi.nlm.nih.gov/pubmed/36059945
http://dx.doi.org/10.3389/fphar.2022.911356