Variation in TAF1 Expression in Female Carrier-Induced Pluripotent Stem Cells and Human Brain Ontogeny Has Implications for Adult Neostriatum Vulnerability in X-Linked Dystonia Parkinsonism

X-linked dystonia-parkinsonism (XDP) is an inherited, X-linked, adult-onset movement disorder characterized by degeneration in the neostriatum. No therapeutics alter disease progression. The mechanisms underlying regional differences in degeneration and adult onset are unknown. Developing therapeuti...

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Detalles Bibliográficos
Autores principales: D’Ignazio, Laura, Jacomini, Ricardo S., Qamar, Bareera, Benjamin, Kynon J. M., Arora, Ria, Sawada, Tomoyo, Evans, Taylor A., Diffenderfer, Kenneth E., Pankonin, Aimee R., Hendriks, William T., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Bragg, D. Cristopher, Paquola, Apua C. M., Erwin, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428949/
https://www.ncbi.nlm.nih.gov/pubmed/35868859
http://dx.doi.org/10.1523/ENEURO.0129-22.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428949/
https://www.ncbi.nlm.nih.gov/pubmed/35868859
http://dx.doi.org/10.1523/ENEURO.0129-22.2022

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