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Variation in TAF1 Expression in Female Carrier-Induced Pluripotent Stem Cells and Human Brain Ontogeny Has Implications for Adult Neostriatum Vulnerability in X-Linked Dystonia Parkinsonism
X-linked dystonia-parkinsonism (XDP) is an inherited, X-linked, adult-onset movement disorder characterized by degeneration in the neostriatum. No therapeutics alter disease progression. The mechanisms underlying regional differences in degeneration and adult onset are unknown. Developing therapeuti...
Autores principales: | D’Ignazio, Laura, Jacomini, Ricardo S., Qamar, Bareera, Benjamin, Kynon J. M., Arora, Ria, Sawada, Tomoyo, Evans, Taylor A., Diffenderfer, Kenneth E., Pankonin, Aimee R., Hendriks, William T., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Bragg, D. Cristopher, Paquola, Apua C. M., Erwin, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428949/ https://www.ncbi.nlm.nih.gov/pubmed/35868859 http://dx.doi.org/10.1523/ENEURO.0129-22.2022 |
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