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Motoneurons innervation determines the distinct gene expressions in multinucleated myofibers

BACKGROUND: Neuromuscular junctions (NMJs) are peripheral synapses connecting motoneurons and skeletal myofibers. At the postsynaptic side in myofibers, acetylcholine receptor (AChR) proteins are clustered by the neuronal agrin signal. Meanwhile, several nuclei in each myofiber are specially enriche...

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Detalles Bibliográficos
Autores principales: Bai, Lei, Tu, Wen-Yo, Xiao, Yatao, Zhang, Kejing, Shen, Chengyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429338/
https://www.ncbi.nlm.nih.gov/pubmed/36042463
http://dx.doi.org/10.1186/s13578-022-00876-6