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Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression

BACKGROUND: Women with a cervicovaginal microbiota dominated by Lactobacillus spp. are at reduced risk of acquiring sexually transmitted infections including HIV, but the biological mechanisms involved remain poorly defined. Here, we performed metaproteomics on vaginal swab samples from young South...

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Detalles Bibliográficos
Autores principales: Delgado-Diaz, David Jose, Jesaveluk, Brianna, Hayward, Joshua A., Tyssen, David, Alisoltani, Arghavan, Potgieter, Matthys, Bell, Liam, Ross, Elizabeth, Iranzadeh, Arash, Allali, Imane, Dabee, Smritee, Barnabas, Shaun, Gamieldien, Hoyam, Blackburn, Jonathan M., Mulder, Nicola, Smith, Steven B., Edwards, Vonetta L., Burgener, Adam D., Bekker, Linda-Gail, Ravel, Jacques, Passmore, Jo-Ann S., Masson, Lindi, Hearps, Anna C., Tachedjian, Gilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429363/
https://www.ncbi.nlm.nih.gov/pubmed/36045402
http://dx.doi.org/10.1186/s40168-022-01337-5