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TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation
BACKGROUND: Recognition of viral invasion by innate antiviral immune system triggers activation of the type I interferon (IFN-I) and proinflammatory signaling pathways. Subsequently, IFN-I induction regulates expression of a group of genes known as IFN-I-stimulated genes (ISGs) to block viral infect...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429444/ https://www.ncbi.nlm.nih.gov/pubmed/36042495 http://dx.doi.org/10.1186/s13578-022-00872-w |