TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation

BACKGROUND: Recognition of viral invasion by innate antiviral immune system triggers activation of the type I interferon (IFN-I) and proinflammatory signaling pathways. Subsequently, IFN-I induction regulates expression of a group of genes known as IFN-I-stimulated genes (ISGs) to block viral infect...

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Detalles Bibliográficos
Autores principales: Zu, Shulong, Li, Chunfeng, Li, Lili, Deng, Yong-Qiang, Chen, Xiang, Luo, Dan, Ye, Qing, Huang, Yi-Jiao, Li, Xiao-Feng, Zhang, Rong-Rong, Sun, Nina, Zhang, Xianqi, Aliyari, Saba R., Nielsen-Saines, Karin, Jung, Jae U., Yang, Heng, Qin, Cheng-Feng, Cheng, Genhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429444/
https://www.ncbi.nlm.nih.gov/pubmed/36042495
http://dx.doi.org/10.1186/s13578-022-00872-w

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