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Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment

Epithelial-mesenchymal transition (EMT), a differentiation process with aberrant changes of tumor cells, is identified as an initial and vital procedure for metastatic processes. Inflammation is a significant inducer of EMT and provides an indispensable target for blocking EMT, however, an anti-infl...

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Detalles Bibliográficos
Autores principales: Jiang, Tianze, Xie, Laozhi, Zhou, Songlei, Liu, Yipu, Huang, Yukun, Mei, Ni, Ma, Fenfen, Gong, Jingru, Gao, Xiaoling, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429706/
https://www.ncbi.nlm.nih.gov/pubmed/36045429
http://dx.doi.org/10.1186/s12951-022-01592-6