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A comprehensive comparison of multilocus association methods with summary statistics in genome-wide association studies

BACKGROUND: Multilocus analysis on a set of single nucleotide polymorphisms (SNPs) pre-assigned within a gene constitutes a valuable complement to single-marker analysis by aggregating data on complex traits in a biologically meaningful way. However, despite the existence of a wide variety of SNP-se...

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Detalles Bibliográficos
Autores principales: Shao, Zhonghe, Wang, Ting, Qiao, Jiahao, Zhang, Yuchen, Huang, Shuiping, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429742/
https://www.ncbi.nlm.nih.gov/pubmed/36042399
http://dx.doi.org/10.1186/s12859-022-04897-3