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SPOP promotes cervical cancer progression by inducing the movement of PD-1 away from PD-L1 in spatial localization

BACKGROUND: Metastasis is a major obstacle in the treatment of cervical cancer (CC), and SPOP-mediated regulatory effects are involved in metastasis. However, the mechanisms have not been fully elucidated. METHODS: Proteomic sequencing and SPOP immunohistochemistry (IHC) were performed for the pelvi...

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Detalles Bibliográficos
Autores principales: Wu, Jiangchun, Wu, Yong, Guo, Qinhao, chen, Siyu, Wang, Simin, Wu, Xiaohua, Zhu, Jun, Ju, Xingzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429754/
https://www.ncbi.nlm.nih.gov/pubmed/36042498
http://dx.doi.org/10.1186/s12967-022-03574-6