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Development and Validation of a Sensitive and Robust Multiplex Antigen Capture Assay to Quantify Streptococcus pneumoniae Serotype-Specific Capsular Polysaccharides in Urine

Streptococcus pneumoniae is a major cause of community-acquired pneumonia (CAP) in young children, older adults, and those with immunocompromised status. Since the introduction of pneumococcal vaccines, the burden of invasive pneumococcal disease caused by vaccine serotypes (STs) has decreased; howe...

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Detalles Bibliográficos
Autores principales: Rajam, Gowrisankar, Zhang, Yuhua, Antonello, Joseph M., Grant-Klein, Rebecca J., Cook, Lauren, Panemangalore, Reshma, Pham, Huy, Cooper, Stephanie, Steinmetz, Thomas D., Nguyen, Jennifer, Pletz, Mathias W., Barten-Neiner, Grit, Murphy, Rocio D., Rubinstein, Leonard J., Nolan, Katrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429912/
https://www.ncbi.nlm.nih.gov/pubmed/35913133
http://dx.doi.org/10.1128/msphere.00114-22