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Tight Complex Formation of the Fumarate Sensing DcuS-DcuR Two-Component System at the Membrane and Target Promoter Search by Free DcuR Diffusion

Signaling of two-component systems by phosphoryl transfer requires interaction of the sensor kinase with the response regulator. Interaction of the C4-dicarboxylate-responsive and membrane-integral sensor kinase DcuS with the response regulator DcuR was studied. In vitro, the cytoplasmic part of Dcu...

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Detalles Bibliográficos
Autores principales: Gencheva, Stefaniya, Dersch, Simon, Surmann, Kristin, Wernet, Mathias, Antelo, Luis, Hammer, Elke, Graumann, Peter L., Hellmann, Nadja, Unden, Gottfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429925/
https://www.ncbi.nlm.nih.gov/pubmed/35862816
http://dx.doi.org/10.1128/msphere.00235-22