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Computational Modeling of Macrophage Iron Sequestration during Host Defense against Aspergillus

Iron is essential to the virulence of Aspergillus species, and restricting iron availability is a critical mechanism of antimicrobial host defense. Macrophages recruited to the site of infection are at the crux of this process, employing multiple intersecting mechanisms to orchestrate iron sequestra...

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Detalles Bibliográficos
Autores principales: Adhikari, Bandita, Scindia, Yogesh, Sordo Vieira, Luis, de Assis Lopes Ribeiro, Henrique, Masison, Joseph, Yang, Ning, Fonseca, Luis L., Wheeler, Matthew, Knapp, Adam C., Mei, Yu, Helba, Brian, Atkinson, Carl, Schroeder, Will, Mehrad, Borna, Laubenbacher, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429928/
https://www.ncbi.nlm.nih.gov/pubmed/35862797
http://dx.doi.org/10.1128/msphere.00074-22