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Modulation of dendritic cell metabolism by an MPLA-adjuvanted allergen product for specific immunotherapy

BACKGROUND: Recently, bacterial components were shown to enhance immune responses by shifting immune cell metabolism towards glycolysis and lactic acid production, also known as the Warburg Effect. Currently, the effect of allergen products for immunotherapy (AIT) and commercial vaccines on immune c...

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Detalles Bibliográficos
Autores principales: Zimmermann, Jennifer, Goretzki, Alexandra, Meier, Clara, Wolfheimer, Sonja, Lin, Yen-Ju, Rainer, Hannah, Krause, Maren, Wedel, Saskia, Spies, Gerd, Führer, Frank, Vieths, Stefan, Scheurer, Stephan, Schülke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430023/
https://www.ncbi.nlm.nih.gov/pubmed/36059475
http://dx.doi.org/10.3389/fimmu.2022.916491