Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii

Coxiella burnetii requires a type IVB secretion system (T4SS) to promote intracellular replication and virulence. We hypothesized that Coxiella employs its T4SS to secrete effectors that enable stealthy colonization of immune cells. To address this, we used RNA sequencing to compare the transcriptio...

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Detalles Bibliográficos
Autores principales: Case, Elizabeth Di Russo, Mahapatra, Saugata, Hoffpauir, Caitlyn T., Konganti, Kranti, Hillhouse, Andrew E., Samuel, James E., Van Schaik, Erin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430109/
https://www.ncbi.nlm.nih.gov/pubmed/35913176
http://dx.doi.org/10.1128/spectrum.02484-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430109/
https://www.ncbi.nlm.nih.gov/pubmed/35913176
http://dx.doi.org/10.1128/spectrum.02484-21

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