Cargando…
Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii
Coxiella burnetii requires a type IVB secretion system (T4SS) to promote intracellular replication and virulence. We hypothesized that Coxiella employs its T4SS to secrete effectors that enable stealthy colonization of immune cells. To address this, we used RNA sequencing to compare the transcriptio...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430109/ https://www.ncbi.nlm.nih.gov/pubmed/35913176 http://dx.doi.org/10.1128/spectrum.02484-21 |