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A 77 Amino Acid Region in the N-Terminal Half of the HSV-1 E3 Ubiquitin Ligase ICP0 Contributes to Counteracting an Established Type 1 Interferon Response

Herpes simplex virus 1 (HSV-1) is a human pathogen capable of establishing lifelong latent infections that can reactivate under stress conditions. A viral immediate early protein that plays important roles in the HSV-1 lytic and latent infections is the viral E3 ubiquitin ligase, ICP0. ICP0 transact...

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Detalles Bibliográficos
Autores principales: Perusina Lanfranca, Mirna, van Loben Sels, Jessica M., Ly, Cindy Y., Grams, Tristan R., Dhummakupt, Adit, Bloom, David C., Davido, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430112/
https://www.ncbi.nlm.nih.gov/pubmed/35730940
http://dx.doi.org/10.1128/spectrum.00593-22