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Immunosuppressant exposure confounds gene expression analysis in systemic lupus erythematosus

OBJECTIVES: The analysis of gene module expression in SLE is emerging as a tool to identify active biological pathways, with the aim of developing targeted therapies for subsets of patients. Detailed information on the effect of immunosuppressants on gene module expression is lacking. We aimed to ex...

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Detalles Bibliográficos
Autores principales: Northcott, Melissa, Gearing, Linden J., Bonin, Julie, Koelmeyer, Rachel, Hoi, Alberta, Hertzog, Paul J., Morand, Eric F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430375/
https://www.ncbi.nlm.nih.gov/pubmed/36059457
http://dx.doi.org/10.3389/fimmu.2022.964263