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Susceptibility of SARS-CoV-2 Omicron Variants to Therapeutic Monoclonal Antibodies: Systematic Review and Meta-analysis

SARS-CoV-2 Omicron variants contain many mutations in its spike receptor-binding domain, the target of all authorized monoclonal antibodies (MAbs). Determining the extent to which Omicron variants reduced MAb susceptibility is critical to preventing and treating COVID-19. We systematically reviewed...

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Detalles Bibliográficos
Autores principales: Tao, Kaiming, Tzou, Philip L., Kosakovsky Pond, Sergei L., Ioannidis, John P. A., Shafer, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430471/
https://www.ncbi.nlm.nih.gov/pubmed/35700134
http://dx.doi.org/10.1128/spectrum.00926-22