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Palladium-catalyzed nucleomethylation of alkynes for synthesis of methylated heteroaromatic compounds

Herein, we disclosed a novel and efficient palladium-catalyzed nucleomethylation of alkynes for the simultaneous construction of the heteroaromatic ring and methyl group. The 3-methylindoles, 3-methylbenzofurans and 4-methylisoquinolines were obtained in moderate to excellent yields. Notably, this m...

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Detalles Bibliográficos
Autores principales: Yang, Xi, Wang, Gang, Ye, Zhi-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430495/
https://www.ncbi.nlm.nih.gov/pubmed/36128232
http://dx.doi.org/10.1039/d2sc03294e