Cargando…

A Small-Molecule Inhibitor of the Anthranilyl-CoA Synthetase PqsA for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa

One of the challenges associated with the treatment of Pseudomonas aeruginosa infections is the high prevalence of multidrug resistance (MDR). Since conventional antibiotics are ineffective at treating such bacterial infections, innovative antibiotics acting upon novel targets or via mechanisms are...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jianwei, Lu, Yaojia, Ye, Fei, Zhang, Hongfang, Zhou, Yonglie, Li, Jiangtao, Wu, Qiang, Xu, Xuewei, Wu, Qihao, Wei, Bin, Zhang, Huawei, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430567/
https://www.ncbi.nlm.nih.gov/pubmed/35856709
http://dx.doi.org/10.1128/spectrum.02764-21