Differential Impact of the rpoB Mutant on Rifampin and Rifabutin Resistance Signatures of Mycobacterium tuberculosis Is Revealed Using a Whole-Genome Sequencing Assay

Drug resistance in Mycobacterium tuberculosis (MTB) has long been a serious health issue worldwide. Most drug-resistant MTB isolates were identified due to treatment failure or in clinical examinations 3~6 months postinfection. In this study, we propose a whole-genome sequencing (WGS) pipeline via t...

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Detalles Bibliográficos
Autores principales: Yu, Ming-Chih, Hung, Ching-Sheng, Huang, Chun-Kai, Wang, Cheng-Hui, Liang, Yu-Chih, Lin, Jung-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430608/
https://www.ncbi.nlm.nih.gov/pubmed/35924839
http://dx.doi.org/10.1128/spectrum.00754-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430608/
https://www.ncbi.nlm.nih.gov/pubmed/35924839
http://dx.doi.org/10.1128/spectrum.00754-22

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