Patient-Derived Antibody Data Yields Development of Broadly Cross-Protective Monoclonal Antibody against ST258 Carbapenem-Resistant Klebsiella pneumoniae

The most pressing challenge for the development of anti-capsular antibodies is maximizing coverage against the heterogenous capsular polysaccharide (CPS) of carbapenem-resistant Klebsiella pneumoniae (CR-Kp). So far, only CR-Kp with wzi154 CPS has been successfully targeted by antibodies. Here, we p...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Kasturi, Motley, Michael P., Boniche-Alfaro, Camila, Bhattacharya, Somanon, Shah, Raj, Ardizzone, Andrew, Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430753/
https://www.ncbi.nlm.nih.gov/pubmed/35862974
http://dx.doi.org/10.1128/spectrum.01760-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430753/
https://www.ncbi.nlm.nih.gov/pubmed/35862974
http://dx.doi.org/10.1128/spectrum.01760-22

Ejemplares similares