Cargando…

Patient-Derived Antibody Data Yields Development of Broadly Cross-Protective Monoclonal Antibody against ST258 Carbapenem-Resistant Klebsiella pneumoniae

The most pressing challenge for the development of anti-capsular antibodies is maximizing coverage against the heterogenous capsular polysaccharide (CPS) of carbapenem-resistant Klebsiella pneumoniae (CR-Kp). So far, only CR-Kp with wzi154 CPS has been successfully targeted by antibodies. Here, we p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Banerjee, Kasturi, Motley, Michael P., Boniche-Alfaro, Camila, Bhattacharya, Somanon, Shah, Raj, Ardizzone, Andrew, Fries, Bettina C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430753/ https://www.ncbi.nlm.nih.gov/pubmed/35862974 http://dx.doi.org/10.1128/spectrum.01760-22

Ejemplares similares

Serum Antibody Responses against Carbapenem-Resistant Klebsiella pneumoniae in Infected Patients
por: Banerjee, Kasturi, et al.
Publicado: (2021)

405. Serum Antibody Responses Against Carbapenem-Resistant Klebsiella pneumoniae in Infected Patients
por: Banerjee, Kasturi, et al.
Publicado: (2019)

The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae
por: Motley, Michael P., et al.
Publicado: (2020)

644. How Antibody Isotype Affects Anti-Capsular Antibody Protection Against Carbapenem-Resistant Klebsiella pneumoniae Infection
por: Motley, Michael, et al.
Publicado: (2018)

Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection
por: Diago-Navarro, Elizabeth, et al.
Publicado: (2018)

Antibody-Mediated Killing of Carbapenem-Resistant ST258 Klebsiella pneumoniae by Human Neutrophils
por: Kobayashi, Scott D., et al.
Publicado: (2018)

Erratum for Diago-Navarro et al., “Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection”
por: Diago-Navarro, Elizabeth, et al.
Publicado: (2018)

271. Epidemiology of ESBL Klebsiella pneumoniae Clonal Group 307 in Stony Brook, NY
por: Glicksberg, Jessica, et al.
Publicado: (2023)

Iron Acquisition and Siderophore Release by Carbapenem-Resistant Sequence Type 258 Klebsiella pneumoniae
por: Holden, Victoria I., et al.
Publicado: (2018)

Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX
por: Shropshire, William C., et al.
Publicado: (2022)

Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against Klebsiella pneumoniae ST258
por: Szijártó, Valéria, et al.
Publicado: (2017)

Transfer of Carbapenem-Resistant Plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in Patient
por: Goren, Moran G., et al.
Publicado: (2010)

Identification of Outer Membrane and Exoproteins of Carbapenem-Resistant Multilocus Sequence Type 258 Klebsiella pneumoniae
por: Brinkworth, Amanda J., et al.
Publicado: (2015)

Genome-Wide Screening for Enteric Colonization Factors in Carbapenem-Resistant ST258 Klebsiella pneumoniae
por: Jung, Hea-Jin, et al.
Publicado: (2019)

OmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo
por: Wong, Joshua L. C., et al.
Publicado: (2019)

Risk Factors and Outcomes for Carbapenem-Resistant Klebsiella pneumoniae Isolation, Stratified by Its Multilocus Sequence Typing: ST258 Versus Non-ST258
por: Dhar, Sorabh, et al.
Publicado: (2016)

L-Arginine Enhances Intracellular Killing of Carbapenem-Resistant Klebsiella pneumoniae ST258 by Murine Neutrophils
por: Peñaloza, Hernán F., et al.
Publicado: (2020)

Immunotherapy against Systemic Fungal Infections Based on Monoclonal Antibodies
por: Boniche, Camila, et al.
Publicado: (2020)

Author Correction: OmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo
por: Wong, Joshua L. C., et al.
Publicado: (2023)

Broadly neutralizing monoclonal antibodies for HIV prevention
por: Miner, Maurine D., et al.
Publicado: (2021)

A New Take on an Old Remedy: Generating Antibodies against Multidrug-Resistant Gram-Negative Bacteria in a Postantibiotic World
por: Motley, Michael P., et al.
Publicado: (2017)

Replicative Aging in Pathogenic Fungi
por: Bhattacharya, Somanon, et al.
Publicado: (2020)

Evolution of Outbreak-Causing Carbapenem-Resistant Klebsiella pneumoniae ST258 at a Tertiary Care Hospital over 8 Years
por: Marsh, Jane W., et al.
Publicado: (2019)

Candidiasis and Mechanisms of Antifungal Resistance
por: Bhattacharya, Somanon, et al.
Publicado: (2020)

An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies
por: Ahmadi, Shirin, et al.
Publicado: (2020)

Epidemic Klebsiella pneumoniae ST258 Is a Hybrid Strain
por: Chen, Liang, et al.
Publicado: (2014)

Replicative Aging in Candida auris Has an Effect on Antifungal Resistance
por: Fries, Bettina C, et al.
Publicado: (2017)

Cryptogenic Liver Abscess Caused by a K1 Serotype Klebsiella pneumoniae Isolate
por: Psonis, John J., et al.
Publicado: (2022)

Pharmacokinetics and Immunogenicity of Broadly Neutralizing HIV Monoclonal Antibodies in Macaques
por: Rosenberg, Yvonne, et al.
Publicado: (2015)

Broad neutralization of SARS-related viruses by human monoclonal antibodies
por: Wec, Anna Z., et al.
Publicado: (2020)

Comment on: CG258 Klebsiella pneumoniae isolates without β-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City
por: Wyres, Kelly L, et al.
Publicado: (2019)

Gene Duplication Associated with Increased Fluconazole Tolerance in Candida auris cells of Advanced Generational Age
por: Bhattacharya, Somanon, et al.
Publicado: (2019)

Emergence of Carbapenemaseproducing Klebsiella Pneumoniae of Sequence type 258 in Michigan, USA
por: Jain, Ruchika, et al.
Publicado: (2013)

An acquired acyltransferase promotes Klebsiella pneumoniae ST258 respiratory infection
por: Ahn, Danielle, et al.
Publicado: (2021)

Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?
por: Gong, Siqi, et al.
Publicado: (2022)

Antibody- Based Immunotherapy Combined With Antimycotic Drug TMP- SMX to Treat Infection With Paracoccidioides brasiliensis
por: Boniche-Alfaro, Camila, et al.
Publicado: (2021)

Human Monoclonal Antibodies Broadly Neutralizing against Influenza B Virus
por: Yasugi, Mayo, et al.
Publicado: (2013)

Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody
por: Tortorici, M. Alejandra, et al.
Publicado: (2021)

621. In vitro Ceftazidime: Avibactam Resistance in Carbapenem-Resistant Enterobacteriaceae Isolates
por: Belal, Maymonah, et al.
Publicado: (2019)

851. Metabolic Changes Contributing to Age-Associated Antifungal Tolerance in Cryptococcus neoformans
por: Yoo, Kyungyoon, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_osn5brbba094t85tjcnuhmt8o1