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Baicalein Acts against Candida albicans by Targeting Eno1 and Inhibiting Glycolysis

Baicalein (BE) is a promising antifungal small-molecule compound with an extended antifungal spectrum, good synergy with fluconazole, and low toxicity, but its target protein and antifungal mechanism remain elusive. In this study, we found that BE can function against Candida albicans by disrupting...

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Detalles Bibliográficos
Autores principales: Li, Liping, Lu, Hui, Zhang, Xuan, Whiteway, Malcolm, Wu, Hao, Tan, Shanlun, Zang, Jianye, Tian, Shujuan, Zhen, Cheng, Meng, Xianlei, Li, Wanqian, Zhang, Dazhi, Zhang, Min, Jiang, Yuanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430770/
https://www.ncbi.nlm.nih.gov/pubmed/35900099
http://dx.doi.org/10.1128/spectrum.02085-22