Transcription Start Site Heterogeneity and Preferential Packaging of Specific Full-Length RNA Species Are Conserved Features of Primate Lentiviruses

HIV-1 must package its RNA genome to generate infectious viruses. Recent studies have revealed that during genome packaging, HIV-1 not only excludes cellular mRNAs, but also distinguishes among full-length viral RNAs. Using NL4-3 and MAL molecular clones, multiple transcription start sites (TSS) wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Rawson, Jonathan M. O., Nikolaitchik, Olga A., Shakya, Saurabh, Keele, Brandon F., Pathak, Vinay K., Hu, Wei-Shau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430795/
https://www.ncbi.nlm.nih.gov/pubmed/35736240
http://dx.doi.org/10.1128/spectrum.01053-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430795/
https://www.ncbi.nlm.nih.gov/pubmed/35736240
http://dx.doi.org/10.1128/spectrum.01053-22

Ejemplares similares