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Transcription Start Site Heterogeneity and Preferential Packaging of Specific Full-Length RNA Species Are Conserved Features of Primate Lentiviruses
HIV-1 must package its RNA genome to generate infectious viruses. Recent studies have revealed that during genome packaging, HIV-1 not only excludes cellular mRNAs, but also distinguishes among full-length viral RNAs. Using NL4-3 and MAL molecular clones, multiple transcription start sites (TSS) wer...
Autores principales: | Rawson, Jonathan M. O., Nikolaitchik, Olga A., Shakya, Saurabh, Keele, Brandon F., Pathak, Vinay K., Hu, Wei-Shau |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430795/ https://www.ncbi.nlm.nih.gov/pubmed/35736240 http://dx.doi.org/10.1128/spectrum.01053-22 |
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