Nitrite Promotes ROS Production to Potentiate Cefoperazone-Sulbactam-Mediated Elimination to Lab-Evolved and Clinical-Evolved Pseudomonas aeruginosa

Cefoperazone-sulbactam (SCF)-resistant Pseudomonas aeruginosa poses a big challenge in the use of SCF to treat infection caused by the pathogen. We have recently shown exogenous nitrite-enabled killing of naturally and artificially evolved Pseudomonas aeruginosa strains (AP-R(CLIN-EVO) and AP-R(LAB-...

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Detalles Bibliográficos
Autores principales: Kuang, Su-fang, Li, Xia, Feng, Ding-Yun, Wu, Wen-Bin, Li, Hui, Peng, Bo, Peng, Xuan-xian, Chen, Zhuang-gui, Zhang, Tian-tuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430864/
https://www.ncbi.nlm.nih.gov/pubmed/35863024
http://dx.doi.org/10.1128/spectrum.02327-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430864/
https://www.ncbi.nlm.nih.gov/pubmed/35863024
http://dx.doi.org/10.1128/spectrum.02327-21

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