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T Cell-Specific STAT1 Expression Promotes Lytic Replication and Supports the Establishment of Gammaherpesvirus Latent Reservoir in Splenic B Cells

Gammaherpesviruses establish lifelong infections in most vertebrate species, including humans and rodents, and are associated with cancers, including B cell lymphomas. While type I and II interferon (IFN) systems of the host are critical for the control of acute and chronic gammaherpesvirus infectio...

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Detalles Bibliográficos
Autores principales: Sylvester, P. A., Jondle, C. N., Schmalzriedt, D. L., Dittel, B. N., Tarakanova, V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430880/
https://www.ncbi.nlm.nih.gov/pubmed/35968944
http://dx.doi.org/10.1128/mbio.02107-22