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Lactobacillus rhamnosus HN001 Ameliorates BEZ235-Induced Intestinal Dysbiosis and Prolongs Cardiac Transplant Survival

Cardiac allograft rejection remains a major factor limiting long-term engraftment after transplantation. A novel phosphoinositide 3-kinase (PI3K)/mTOR dual inhibitor, BEZ235, prolonged cardiac allograft survival by effectively suppressing activation of the PI3K/serine/threonine kinase (AKT)/mTOR pat...

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Detalles Bibliográficos
Autores principales: Miao, Xiaolong, Jiang, Yuancong, Kong, Deqiang, Wu, Zelai, Liu, Han, Ye, Xiaolin, Gong, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430965/
https://www.ncbi.nlm.nih.gov/pubmed/35862958
http://dx.doi.org/10.1128/spectrum.00794-22