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Pathogen-Specific Bactericidal Method Mediated by Conjugative Delivery of CRISPR-Cas13a Targeting Bacterial Endogenous Transcripts

The emergence of antibiotic-resistant bacteria threatens public health, and the use of broad-spectrum antibiotics often leads to unintended consequences, including disturbing the beneficial gut microbiota and resulting in secondary diseases. Therefore, developing a novel strategy that specifically k...

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Detalles Bibliográficos
Autores principales: Song, Zihao, Yu, Yue, Bai, Xinpeng, Jia, Yiguo, Tian, Jiayi, Gu, Kui, Zhao, Mengyu, Zhou, Changyu, Zhang, Xiangyu, Wang, Hongning, Tang, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430969/
https://www.ncbi.nlm.nih.gov/pubmed/35950861
http://dx.doi.org/10.1128/spectrum.01300-22