BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis

Moloney murine leukemia virus (MLV) infects BALB/c mice and induces T-cell lymphoma in mice. Retroviral integration is mediated by the interaction of the MLV integrase (IN) with members of the bromodomain and extraterminal motif (BET) protein family (BRD2, BRD3, and BRD4). The introduction of the W3...

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Detalles Bibliográficos
Autores principales: Nombela, Ivan, Michiels, Martine, Van Looveren, Dominique, Marcelis, Lukas, el Ashkar, Sara, Van Belle, Siska, Bruggemans, Anne, Tousseyn, Thomas, Schwaller, Jürg, Christ, Frauke, Gijsbers, Rik, De Rijck, Jan, Debyser, Zeger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431007/
https://www.ncbi.nlm.nih.gov/pubmed/35852337
http://dx.doi.org/10.1128/spectrum.01478-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431007/
https://www.ncbi.nlm.nih.gov/pubmed/35852337
http://dx.doi.org/10.1128/spectrum.01478-22

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