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Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza
Influenza A virus (IAV) coopts numerous host factors for efficient replication. The cysteine protease cathepsin W (CTSW) has been identified as one host factor required for IAV entry, specifically for the escape of IAVs from late endosomes. However, the substrate specificity of CTSW and the proviral...
Autores principales: | Günther, Sira C., Martínez-Romero, Carles, Sempere Borau, Milagros, Pham, Christine T. N., García-Sastre, Adolfo, Stertz, Silke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431242/ https://www.ncbi.nlm.nih.gov/pubmed/35867415 http://dx.doi.org/10.1128/spectrum.00921-22 |
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