Emergence of a Novel Plasmid-Mediated Tigecycline Resistance Gene Cluster, tmexCD4-toprJ4, in Klebsiella quasipneumoniae and Enterobacter roggenkampii

The occurrence of transferable tigecycline resistance determinants, tmexCD1-toprJ1, tmexCD2-toprJ2, tmexCD3-toprJ1b, and multiple tet(A) and tet(X) variants, presents an unprecedented challenge to clinical therapeutic options. tmexCD-toprJ-like gene clusters can mediate multidrug resistance and have...

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Detalles Bibliográficos
Autores principales: Gao, Xun, Wang, Chengzhen, Lv, Luchao, He, Xiaotong, Cai, Zhongpeng, He, Wanyun, Li, Tong, Liu, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431256/
https://www.ncbi.nlm.nih.gov/pubmed/35862955
http://dx.doi.org/10.1128/spectrum.01094-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431256/
https://www.ncbi.nlm.nih.gov/pubmed/35862955
http://dx.doi.org/10.1128/spectrum.01094-22

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