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Emergence of a Novel Plasmid-Mediated Tigecycline Resistance Gene Cluster, tmexCD4-toprJ4, in Klebsiella quasipneumoniae and Enterobacter roggenkampii
The occurrence of transferable tigecycline resistance determinants, tmexCD1-toprJ1, tmexCD2-toprJ2, tmexCD3-toprJ1b, and multiple tet(A) and tet(X) variants, presents an unprecedented challenge to clinical therapeutic options. tmexCD-toprJ-like gene clusters can mediate multidrug resistance and have...
Autores principales: | Gao, Xun, Wang, Chengzhen, Lv, Luchao, He, Xiaotong, Cai, Zhongpeng, He, Wanyun, Li, Tong, Liu, Jian-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431256/ https://www.ncbi.nlm.nih.gov/pubmed/35862955 http://dx.doi.org/10.1128/spectrum.01094-22 |
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